Pancreatic paraganglioma a differential diagnosis of pancreatic mass. Case report
DOI:
https://doi.org/10.53903/01212095.108Keywords:
Pancreas, Paraganglioma, Incidental findings, Abdominal painAbstract
Paraganglioma is a rare neoplasm that arises from the chromaffin cells of the autonomic nervous system. Paragangliomas that originate in the pancreas are even rarer with a very low rate of malignancy. Given the small number of cases documented so far, few radiologic characteristics are known about them and they are usually incidental findings in routine imaging studies. The vast majority of pancreatic paragangliomas do not secrete catecholamines and are called “nonfunctioning” and can cause symptoms such as abdominal pain or be asymptomatic. There are only two cases of catecholamine-secreting or “functioning” paragangliomas documented to date, presenting with headache, hypertension, and palpitations. Pancreatic paragangliomas reported so far have occurred in multiple locations in the pancreas, including the head, body, and tail. The risk of malignant transformation of paragangliomas makes surgical resection the treatment of choice, and aggressive surgery and close postoperative follow-up are mandatory to achieve disease-free survival. In this study we present the case of an 83-year-old patient with a diagnosis of non-functioning paraganglioma confirmed by pathological anatomy, located in the cephalic portion of the pancreas. We also review relevant literature.
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References
Al-Jiffry BO, Alnemary Y, Khayat SH, Haiba M, Hatem M. Malignant extraadrenal pancreatic paraganglioma: case report and literature review. BMC Cancer. 2013;13:486.
Sangster G, Do D, Previgliano C, Li B, LaFrance D, Heldmann M. Primary retroperitoneal paraganglioma simulating a pancreatic mass: A case report and review of the literature. HPB Surg. 2010, Article ID 645728, 4 pages.
Park JS, Min SJ, Min SK, Choi JA. Pancreatic paraganglioma: a case report and literature review. Investig Magn Reson Imaging. 2021;25(1):47-52.
Manning MA, Paal EE, Srivastava A, Mortele KJ. Nonepithelial neoplasms of the pancreas, Part 2: malignant tumors and tumors of uncertain malignant potential from the radiologic pathology archives. RadioGraphics. 2018;38(4):1047-72.
Wang W, Qin Y, Zhang H, Chen K, Liu Z, Zheng S. A rare case of retroperitoneal paraganglioma located in the neck of the pancreas: a case report and literature review. Gland Surgery. 2021;10(4):1523.
Kim SY, Byun JH, Choi G, Yu E, Choi EK, Park SH, et al. A case of primary paraganglioma that arose in the pancreas: the color Doppler ultrasonography and Dynamic CT features. Korean J Radiol. 2008;9:S18-21.
Khanna L, Prasad S, Sunnapwar A, Kondapaneni S, Dasyam A, Tammisetti V, et al. Pancreatic neuroendocrine neoplasms: 2020 update on pathologic and imaging findings and classification. RadioGraphics. 2020;40(5):1240-62.
Lin S, Peng L, Huang S, Li Y, Xiao W. Primary pancreatic paraganglioma: a case report and literature review. World J Surg Oncol. 2016;14:19.
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