Hepatic sinusoidal obstructive syndrome due to the consumption of alkyl nitrites. A case report

Authors

  • Julia Andrea Rodríguez Hospital Universitarios San Ignacio
  • Diana Marcela Romero Hospital Universitario San Ignacio
  • Liliana Arias Hospital Universitario San Ignacio

DOI:

https://doi.org/10.53903/01212095.174

Keywords:

Hypertension, portal, Abdominal pain, Magnetic resonance imaging

Abstract

The sinusoidal obstructive syndrome is a cause of post sinusoidal hepatic portal hypertension, which occurs because of hepatotoxic agents that damage the endothelium of the central venule, resulting in obstruction of the blood flow and congestion causing post sinusoidal portal hypertension. This pathology is very rare, and its main etiology is hematopoietic cell transplantation, although other etiologies have been described such as the use of hepatotoxic agents that include chemotherapy, radiotherapy, and intake of alkaloids. The clinical presentation of these patients does not vary significantly with respect to the other causes of portal hypertension, reason why diagnostic images play a key role in the initial approach of these patients. We present the case of 16 years old patient with portal hypertension due to the consumption of alkyl nitrites.

Downloads

Download data is not yet available.

References

Ravaioli F, Colecchia A, Alemanni LV. Role of imaging techniques in liver venoocclusive disease diagnosis: recent advances and literature review. Expert Rev Gastroenterol Hepatol. 2019;13(5):463-84. DOI:10.1080/17474124.2019.1588111

Roskams T, Baptista A, Bianchi L. Histopathology of portal hypertension: a practical guideline. Histopathology. 2003;42:2-13.

Mortelé KJ, Vlierberghe HV, Wiesner W. Hepatic veno occlusive disease: MRI findings. Abdom Imaging. 2002;27:523-6. DOI: 10.1007/s00261-001-0097-5

Van den Bosch MA, Van Hoe L. MR imaging findings in two patients with hepatic venoocclusive disease following bone marrow transplantation. Eur Radiol. 2000;10:1290-3.

Mehmet S, Mortelé K, Binkert C, et al. CT features of hepatic venooclusive disease and Hepatic Graft-versus-host disease in patients after hematopoietic stem cell transplantation. AJR. 2006;186(6):1497-501. doi: 10.2214/AJR.05.0539.

Published

2022-06-30

How to Cite

(1)
Rodríguez , J. A.; Romero, D. M.; Arias, L. Hepatic Sinusoidal Obstructive Syndrome Due to the Consumption of Alkyl Nitrites. A Case Report. Rev. colomb. radiol. 2022, 33, 5782-5784.

Issue

Section

Case reports
Crossref Cited-by logo
QR Code